Academic Title(s)

• Research Assistant Professor of Anatomy and Neurobiology

Bio

I received my master’s degree in biotechnology from Aligarh Muslim University, Aligarh, India and PhD from the department of Microbiology and Cell Biology, from Indian Institute of Science, Bangalore, India. After my doctoral study, I moved to International Centre for Genetic Engineering and Biotechnology, New Delhi for my first postdoc where I worked on the role of micro-RNA in the pathogenesis of HIV-1. After that I moved to NEOMED in 2014 and joined Prof Dr Tariq M Haqqi (Haqqi lab) as a postdoc. Since then I have been working on the understanding of the molecular pathway(s) involved in the pathogenesis of Osteoarthritis (OA) and identification of novel therapeutic target(s) for its treatment.

Educational Background

• Bachelor of Science, Biology, Dr R.M.L. Avadh university, Faizabad, UP, India, 2004
• Master of Science, Biotechnology, Aligarh Muslim University, Aligarh, UP, India, 2007
• Doctor of Philosophy, Microbiology and Cell Biology, Indian Institute of Science, Bangalore, KA, India, 2013

Presentations

• 2018, ORS Great Lakes/Midwest Regional Sympoium, Ann Arbor, MI
• 2018, EULAR Congress, Amsterdam, Netherlands
• 2017, OARSI World Congress, Las Vegas, NV

Publications

• Genetic Inactivation of ZCCHC6 Suppresses Interleukin-6 Expression and Reduces the Severity of Experimental Osteoarthritis in Mice
• Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes
• Interleukin-1β induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes
• Butein Activates Autophagy Through AMPK/TSC2/ULK1/mTOR Pathway to Inhibit IL-6 Expression in IL-1β Stimulated Human Chondrocytes
• A standardized extract of Butea monosperma (Lam.) flowers suppresses the IL-1β-induced expression of IL-6 and matrix-metalloproteases by activating autophagy in human osteoarthritis chondrocytes